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Bioactives from organ culture

Background

These projects aimed to develop a new bioprocess that amplifies yields of commercially valuable bioactive products from 'farmed' animal organs.

Research

The first project (A.BIT.0008) aimed to develop new bioprocesses by amplification of the yields of commercially valuable bioactive products from cultured animal organs. In phase 1 of this project, up to 43-fold amplification of the levels of certain bioactives was reported in small- scale laboratory trials. Phase 2 focused on scale-up to commercially competitive levels using alkaline phosphatase (AP) as a model bioactive. An external consultant, Dr Gareth Forde, analysed the production process and generated an engineering-based economic model and sensitivity analysis for the manufacture of bioactives using the organ culture method developed.

Outcomes

The detailed technical and cost benefit analysis concluded that the technology was neither commercially or technically viable, and further investment was terminated by MLA. 

 

Downloads

Contracts

Contract No. Title Start date End date Funding type
A.BIM.0030
Commercial opportunity analysis: Transient transformation of animal-derived biomass
15/12/2011 05/09/2012
Industry
A.BIT.0017
Transient Production of therapeutic compounds
20/05/2011 07/09/2012
Industry
A.BIT.0008
Production of bioactives using in vitro culture of cells from organs sourced from the meat processing industry - Phase II
15/06/2009 13/08/2011
Industry
A.BIT.0015
IVCC commercialisation strategy development
07/04/2011 29/07/2011
Industry
A.BIM.0035
Cell Culture Manufacturing Capacity: Trends and Outlook Through 2013
19/08/2011 31/10/2011
Industry CMA
A.BIT.0018
Protocol Development & technical feasibility evaluation of transient expression
01/04/2011 31/01/2012
Industry
A.BIT.0001
Production of bioactives using in vitro culture of cells from organs sourced from the meat processing industry
02/01/2007 30/05/2009
Industry

This page was last updated on 06/07/2018

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